ESBG LAB

We are an interdisciplinary research group leveraging advances in artificial intelligence, bioinformatics, and systems biochemistry to map the complex relationships connecting protein sequence, structure, function, and evolution. We focus on biomedically important protein families such as protein kinases, glycosyltransferases, and ion channels that are causally associated with human diseases such as cancer, diabetes, and neurodegenerative disorders. We aim to develop personalized therapeutic strategies for these diseases based on a deeper understanding of how these proteins work in normal and disease states.

If you are interested in joining our lab, please get in touch with Dr. Kannan to discuss current openings and opportunities.

ONGOING RESEARCH

This is an overview of current research in the lab. You can click on each title for detailed information.

Mapping genome-phenome relationships in large protein families

Proteins are essential for life and their malfunctions are linked to diseases. Our lab studies these complex molecules to develop new therapies.

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AI and Deep learning models for biochemical applications

AI is revolutionizing biochemistry by analyzing protein sequences, like a code, to predict changes, group enzymes, and classify proteins.

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Evolutionary Data Analytics

Huge datasets from "omic" studies hold promise for protein research, but require user-friendly tools to analyze this complex information. Our lab builds user friendly tools for researchers.

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News


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2025-07-14

Saber got a Clinical Assistant Professor position at Georgia State University(GSU)!!


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2025-06-01

Jason secured a MD-PHD position at Renaissance School of Medicine at Stony Brook University!!


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2025-04-03

Dr. Kannan was awarded Distinguished Research Professor at UGA for 2025!!


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2025-04-01

Neha received the Emerging Student Leader of the Year 2025 from International Student Life(ISL) at UGA !!


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2024-08-12

Congratulations to Brady for winning the best presentation award at the EMBO Pseudoenzymes meeting in Girona, Spain


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2024-04-10

Grace Watterson receives NSF GRFP fellowship!


PEOPLE

Meet our team members

Dr. Natarajan Kannan

Dr. Natarajan Kannan

Professor and Georgia Coalition Distinguished Scholar

Professor and Georgia Coalition Distinguished Scholar

Ansley Applestone 

Ansley Applestone 

Undergraduate Research Assistant
Biochemistry

Ryan Bhowmik

Ryan Bhowmik

Graduate Research Assistant
Bioinformatics

Ruili Fang

Ruili Fang

Graduate Research Assistant
Computer Science

Emory Gandy

Emory Gandy

Undergraduate Research Assistant
Biochemistry

Nathan Gravel

Nathan Gravel

Graduate Research Assistant
Bioinformatics

Neha Gupta

Neha Gupta

Graduate Research Assistant
Bioinformatics

Kamaleldin Hassan Kamaleldin

Kamaleldin Hassan Kamaleldin

NSF Research Experiences for Undergraduate(REU) Scholar
Bioinformatics

Dr. Samiksha Katiyar

Dr. Samiksha Katiyar

Research Scientist
Bioinformatics

Rezwan Mahmud

Rezwan Mahmud

Graduate Research Assistant
Computer Science

Lan Na

Lan Na

Postdoc
Biochemistry

Anup Kumar Prasad

Anup Kumar Prasad

Postdoc
Biochemistry

Saber Soleymani

Saber Soleymani

Postdoc
Computer Science

Alumni

Ishan Aggarwal

Ishan Aggarwal

Undergraduate Research Assistant
Biochemistry

George Bendzunas

George Bendzunas

Postdoc
Biochemistry

Claire Bunn

Claire Bunn

Undergraduate Research Assistant
Genetics

Rayna Carter

Rayna Carter

Undergraduate Research Assistant
Biochemistry

Shima Dastgheyb

Shima Dastgheyb

Graduate Research Assistant
Computer Science

Ayda Farhadi

Ayda Farhadi

Graduate Research Assistant
Computer Science

Navid Hashemi

Navid Hashemi

Graduate Research Assistant
Computer Science

Liang-Chin Huang

Liang-Chin Huang

Graduate Research Assistant
Bioinformatics

Nathan Kleber

Nathan Kleber

Undergraduate Research Assistant
Biochemistry

Hyunjin Annie Kwon

Hyunjin Annie Kwon

Graduate Research Assistant
Bioinformatics

Andrew Lamb

Andrew Lamb

Undergraduate Research Assistant
Biochemistry

Jason Lu

Jason Lu

Undergraduate Research Assistant
Bioinformatics

Daniel McSkimming

Daniel McSkimming

Graduate Research Assistant
Bioinformatics

Smita Mohanty

Smita Mohanty

Postdoc
Biochemistry

Tuan Nguyen

Tuan Nguyen

Undergraduate Research Assistant
Biochemistry

Brady O'Boyle

Brady O'Boyle

Graduate Research Assistant
Biochemistry

Krishnadev Oruganty

Krishnadev Oruganty

Postdoc
Biochemistry

Priyanka Parikh

Priyanka Parikh

Undergraduate Research Assistant
Biochemistry

Parnian Rahimi

Parnian Rahimi

Graduate Research Assistant
Bioinformatics

Zheng Ruan

Zheng Ruan

Graduate Research Assistant
Bioinformatics

 Farzaneh Saadati

Farzaneh Saadati

Graduate Research Assistant
Computer Science

Mariah Salcedo

Mariah Salcedo

Graduate Research Assistant
Bioinformatics

Carlos E Sanz

Carlos E Sanz

Postdoc
Biochemistry

Steven Thomas Scott

Steven Thomas Scott

Undergraduate Research Assistant
Genetics

Tej Shidhaye

Tej Shidhaye

Undergraduate Research Assistant
Biochemistry

Safal Shrestha

Safal Shrestha

Postdoc
Bioinformatics

Eric Talevich

Eric Talevich

Graduate Research Assistant
Bioinformatics

Rahil Taujale

Rahil Taujale

Graduate Research Assistant
Bioinformatics

Niral Thaker

Niral Thaker

Undergraduate Research Assistant
Biochemistry

Aarya Venkat

Aarya Venkat

Graduate Research Assistant
Biochemistry

Grace Watterson

Grace Watterson

Undergraduate Research Assistant
Biochemistry

Wayland Yeung

Wayland Yeung

Graduate Research Assistant
Bioinformatics

Zhongliang Zhou

Zhongliang Zhou

Graduate Research Assistant
Computer Science

COLLABORATORS

Frank Sicheri

(Mount Sinai Hospital)

Alexandra Newton

(UC San Diego)

Susan S. Taylor

(UC San Diego)

Gerard Manning

(Genentech)

Christian Doerig

(Monash University)

Patrick Eyers

(University of Liverpool)

Contact

Lab picture