Welcome to ESBG.
Research in our group is directed toward understanding the design principles of cellular signaling proteins using systems biology approaches.
We are currently focusing on large protein families such as protein kinases and phosphatases that have evolved numerous regulatory mechanisms to control major signal transduction pathways. We are using a combination of computational and experimental techniques to obtain an in-depth understanding of the evolutionary rules that govern the structure and regulation of these proteins. Our ultimate goal is to predict how genomic alterations in these proteins lead to human diseases such as cancer.
See the research page for more about what we do.
Latest news
New publication in BMC Evol Biol surveys kinases in pathogenic protozoa
Nov. 2, 2011
Eric Talevich, Amar Mirza and Dr. Natarajan Kannan have published a new research article in the journal BMC Evolutionary Biology titled "Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa." The study examines the kinomes and individual ePK families in the malaria pathogen and its relatives, from both evolutionary and structural perspectives.
Krishnadev wins the 2011 Harry Peck Research Award
Oct. 15, 2011
The UGA Department of Biochemistry and Molecular Biology presented the 2011 Harry Peck Research Award to postdoctoral fellow Dr. Krishnadev Oruganty at this year's Fall Retreat.
Amar Mirza named 2011 Goldwater Scholar
March 30, 2011
The Barry M. Goldwater Scholarship and Excellence In Education Foundation awarded its prestigious 2011 Goldwater Scholarship to Amar Mirza and two other UGA students, from among over 1000 undergraduates nominated by university faculty nationwide. You're a star, Amar!