Welcome to ESBG.
Research in our group is directed toward understanding the design principles of cellular signaling proteins using systems biology approaches.
We are currently focusing on large protein families such as protein kinases and phosphatases that have evolved numerous regulatory mechanisms to control major signal transduction pathways. We are using a variety of techniques including comparative genomics, structural bioinformatics and molecular dynamics simulations to obtain an in-depth understanding of the evolutionary rules that govern the structure and regulation of these proteins. Our ultimate goal is to predict how genomic alterations in these proteins lead to human diseases such as cancer.
See the research page for more about what we do.
Latest news
Dr. Kannan named Georgia Cancer Coalition Distinguished Cancer Scholar
June 23, 2009
The Georgia Cancer Coalition (GCC) has named Dr. Kannan a Distinguished Cancer Scholar. This award is given by GCC to clinicians and scientists who are engaged in the most promising areas of cancer research in the state of Georgia.
NESCent selects Eric Talevich for Summer of Code 2009
Apr. 20, 2009
Eric Talevich's project proposal for the upcoming Google Summer of Code has been accepted, under the umbrella of the National Evolutionary Synthesis Center. Eric will be building a parser and object representation for the emerging phyloXML format for phylogenetic trees, integrating with the Biopython toolkit. (Project abstract, Open Bioinformatics Foundation announcement).